NU 1085

Catalog No.: A28994
PARP Inhibitor
NU 1085 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor with an impressive Ki of 6 nM. This compound exhibits significant cytotoxicity towards cancer cells, with an LC50 between 83-94 μM. Additionally, NU 1085 has the potential to enhance the anticancer effects of Temozolomide, making it a valuable tool for cancer research, particularly in the study of lung cancer and other malignancies.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNU 1085 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor with an impressive Ki of 6 nM. This compound exhibits significant cytotoxicity towards cancer cells, with an LC50 between 83-94 μM. Additionally, NU 1085 has the potential to enhance the anticancer effects of Temozolomide, making it a valuable tool for cancer research, particularly in the study of lung cancer and other malignancies.
Product Information
Catalog NumA28994
FormulaC14H11N3O2
Molecular Weight253.26
CAS Number188106-83-4
SMILESNC(C1=C2C(NC(C3=CC=C(O)C=C3)=N2)=CC=C1)=O
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