Signaling Pathway
Product type
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| Discription | NU-7441 (KU-57788) is a potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor. The IC50 values are 14, 1700, 5000, >100000 and >100000 nM for DNA-PK, mTOR, PI 3-K, ATM and ATR respectively. | |||||
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| Cell Research |
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| Catalog Num | A11098 |
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| Formula | C25H19NO3S |
| Molecular Weight | 413.5 |
| CAS Number | 503468-95-9 |
| SMILES | C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC5=C4SC6=CC=CC=C56 |
| Synonyms | NU7441, KU57788 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | Warmed: 4 mg/mL (9.67 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 5% DMSO+30% PEG 300+5% Tween 80+ddH2O | 1 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.18 mL | 120.92 mL | 241.84 mL |
| 0.5 mM | 4.84 mL | 24.18 mL | 48.37 mL |
| 1 mM | 2.42 mL | 12.09 mL | 24.18 mL |
| 5 mM | 0.48 mL | 2.42 mL | 4.84 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
