NU-7441 (KU-57788)

Catalog No.: A11098

DNA-PK inhibitor

NU-7441 (KU-57788) Chemical Structure

CAS NO. 503468-95-9

NU-7441 (KU-57788) is a potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor. The IC50 values are 14, 1700, 5000, >100000 and >100000 nM for DNA-PK, mTOR, PI 3-K, ATM and ATR respectively.

Availability: In stock

Package Price Qty
5 mg
$50.00
10 mg
$90.00
50 mg
$180.00
100 mg
$300.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

NU-7441 (KU-57788) is a potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor. The IC50 values are 14, 1700, 5000, >100000 and >100000 nM for DNA-PK, mTOR, PI 3-K, ATM and ATR respectively.
In vitro DMSO 3 mg/mL (7.25 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.18 mL 120.92 mL 241.84 mL
0.5 mM 4.84 mL 24.18 mL 48.37 mL
1 mM 2.42 mL 12.09 mL 24.18 mL
5 mM 0.48 mL 2.42 mL 4.84 mL

*The above data is based on the productmolecular weight 413.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11098
Actions Inhibitor
M. Wt 413.5
Formula C25H19NO3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 503468-95-9
Synonyms NU7441, KU57788
SMILES C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC5=C4SC6=CC=CC=C56

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