NU-7441 (KU-57788)

NU-7441 (KU-57788) is a potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor. The IC50 values are 14, 1700, 5000, >100000 and >100000 nM for DNA-PK, mTOR, PI 3-K, ATM and ATR respectively.
Grouped product items
Product Name Price Stock Qty
NU-7441 (KU-57788) 5mg
$50.00
In stock
NU-7441 (KU-57788) 10mg
$90.00
In stock
NU-7441 (KU-57788) 50mg
$180.00
In stock
NU-7441 (KU-57788) 100mg
$300.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Adooq's NU-7441 (KU-57788) has been cited by 6 publications
  • Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418
  • Ryo Sakasai, .et al. , Biochem Biophys Res Commun, 2023, Aug 6;668:42-48 PMID: 37244033
  • Shahar Biechonski, .et al. , Sci Rep, 2018, Apr 17 PMID: 29666389
  • Ihara M, .et al. , J Radiat Res, 2018, Nov 23 PMID: 30476230
  • Chwastek J, .et al. , Int J Biochem Cell Biol, 2017, Jun;87:38-53 PMID: 28341201
  • Masaaki Yanai, .et al. , Yonago Acta Med, 2017, Mar; 60(1): 9-15 PMID: 28331416
  • Biological Activity
    Discription NU-7441 (KU-57788) is a potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor. The IC50 values are 14, 1700, 5000, >100000 and >100000 nM for DNA-PK, mTOR, PI 3-K, ATM and ATR respectively.
    Targets
    Target Value
    Product Information
    Catalog Num A11098
    Formula C25H19NO3S
    Molecular Weight 413.5
    CAS Number 503468-95-9
    SMILES C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC5=C4SC6=CC=CC=C56
    Synonyms NU7441, KU57788
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 4 mg/mL (9.67 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5% DMSO+30% PEG 300+5% Tween 80+ddH2O 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 24.18 mL 120.92 mL 241.84 mL
    0.5 mM 4.84 mL 24.18 mL 48.37 mL
    1 mM 2.42 mL 12.09 mL 24.18 mL
    5 mM 0.48 mL 2.42 mL 4.84 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    Keywords: buy NU-7441 (KU-57788) | NU-7441 (KU-57788) Supplier | purchase NU-7441 (KU-57788) | NU-7441 (KU-57788) cost | NU-7441 (KU-57788) manufacturer | order NU-7441 (KU-57788) | NU-7441 (KU-57788) distributor | buy 503468-95-9 | 503468-95-9 Supplier | purchase 503468-95-9 | 503468-95-9 cost | 503468-95-9 manufacturer | order 503468-95-9 | 503468-95-9 distributor