NU7026

Catalog No.: A12752

DNA-PK inhibitor

NU7026

NU7026 Chemical Structure

CAS NO. 154447-35-5

NU7026 is a novel DNA-dependent protein kinase inhibitor that potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $50.00

Special Price $40.00

25 mg

Regular Price: $100.00

Special Price $80.00

50 mg

Regular Price: $160.00

Special Price $128.00

100 mg

Regular Price: $280.00

Special Price $224.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

NU7026 is a novel DNA-dependent protein kinase inhibitor that potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia.
Targets
DNA-PK (Cell-free assay) PI3K (Cell-free assay) ATM (Cell-free assay) ATR (Cell-free assay)
0.23 μM13 μM>100 μM>100 μM
In vitro (25°C) DMSO 1 mg/mL (3.55 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.55 mL 177.74 mL 355.48 mL
0.5 mM 7.11 mL 35.55 mL 71.1 mL
1 mM 3.55 mL 17.77 mL 35.55 mL
5 mM 0.71 mL 3.55 mL 7.11 mL

*The above data is based on the productmolecular weight 281.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A12752
Actions Inhibitor
M. Wt 281.31
Formula C17H15NO3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 154447-35-5
Synonyms NU 7026, NU-7026
SMILES C1COCCN1C2=CC(=O)C3=C(O2)C4=CC=CC=C4C=C3

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