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DNA-PK inhibitor

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Catalog No. A12752

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
NU7026 10mg A12752-10

Regular Price: €47.50

Special Price: €42.75

NU7026 25mg A12752-25

Regular Price: €95.00

Special Price: €85.50

NU7026 50mg A12752-50

Regular Price: €152.00

Special Price: €136.80

NU7026 100mg A12752-100

Regular Price: €266.00

Special Price: €239.40

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

NU7026 is a novel DNA-dependent protein kinase inhibitor that potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia.


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Publications citing Adooq Products
NU7026 Citations (1)
  • Velichko AK, .et al. Hypoosmotic stress induces R loop formation in nucleoli and ATR/ATM-dependent silencing of nucleolar transcription, Nucleic Acids Res, 2019, May 22. pii: gkz436 PMID: 31114877

Chemical Information

Catalog Num A12752
Actions Inhibitor
M. Wt 281.31
Formula C17H15NO3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 154447-35-5
Synonyms NU 7026, NU-7026

Biological Activity

NU7026 is a novel DNA-dependent protein kinase inhibitor that potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia.
DNA-PK (Cell-free assay) PI3K (Cell-free assay) ATM (Cell-free assay) ATR (Cell-free assay)
0.23 μM13 μM>100 μM>100 μM


Solubility (25°C) * In vitro DMSO 1 mg/mL (3.55 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.55 mL 177.74 mL 355.48mL
0.5 mM 7.11 mL 35.55 mL 71.1 mL
1 mM 3.55 mL 17.77 mL 35.55 mL
5 mM 0.71 mL 3.55 mL 7.11 mL

*The above data is based on the productmolecular weight 281.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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