Fig. 1 · Structure
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Nudol
Anti-cancer Agent
Nudol is a phenanthrene compound that exhibits anti-cancer activity primarily by inhibiting matrix metalloproteinases MMP-2 and MMP-9, with inhibitory constants of 988.9 nM and 1.76 μM, respectively. This compound effectively reduces cell proliferation and induces apoptosis in cancer cells. Nudol is valuable for research applications in various cancer types, including osteosarcoma.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 86630-46-8 |
| Applications | Anti-cancer Agent |
| Formula | C16H14O4 |
| Molecular Weight | 270.28 |
| SMILES | OC1=C(OC)C(OC)=C2C3=CC=C(O)C=C3C=CC2=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.