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Nurr1 agonist 5

Nurr1 Agonist

Nurr1 Agonist 5 is a selective agonist of the neuroprotective transcription factor Nurr1, exhibiting a Kd of 0.5 μM and an EC50 of 3 μM. This compound is instrumental in modulating neuroinflammatory responses and promoting the survival of dopaminergic neurons. Research applications include studies on neurodegenerative diseases and the exploration of therapeutic strategies targeting Nurr1 pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	3033875-32-7
Applications	Nurr1 Agonist
Formula	C₁₉H₁₉Cl₂N₃O₂
Molecular Weight	392.28
SMILES	ClC1=C(C=C2C(C=CN2)=C1)C(NC3=C(C=CC(Cl)=C3)OCCN(C)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.