Fig. 1 · Structure
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NusB-NusE interaction IN-1
NusB-NusE interaction Inhibitor
NusB-NusE interaction IN-1 is a specific inhibitor of the protein-protein interaction between NusB and NusE. It demonstrates growth inhibitory activity against the Gram-positive bacterium Bacillus subtilis, with an IC50 of 6.1 μM, and also affects growth in the Gram-negative Escherichia coli. This compound is valuable for researching transcription regulation and bacterial growth mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 125966-81-6 |
| Applications | NusB-NusE interaction Inhibitor |
| Formula | C28H28N4O7S |
| Molecular Weight | 564.61 |
| SMILES | O=C(NC1=CC=C(C=C1)S(=O)(=O)NC=2N=C(C=C(N2)C=3C=CC(OC)=CC3OC)C=4C=CC(OC)=C(OC)C4)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.