Nutlin-3

Name: Nutlin-3
SKU: A10657
Price: 45 USD
Rating: 5 (4 reviews)

Catalog No.: A10657

Mdm2 antagonist

Adooq's Nutlin-3 has been cited by 4 publications

MDM2 antagonist nutlin-3 is a potent inducer of apoptosis.

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Grouped product items
Size	Price	Stock
2mg	$45.00	In stock
5mg	$60.00	In stock
10mg	$110.00	In stock
25mg	$195.00	In stock
50mg	$355.00	In stock
100mg	$515.00	In stock
*10mM 1mL in DMSO**	$105.00	In stock
Bulk Size	Bulk Discount

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Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's Nutlin-3 has been cited by 4 publications

Maxime Parisotto, .et al. , J Exp Med, 2018, Jun 4; 215(6): 1749-1763 PMID: 29743291

Ohmuro-Matsuyama Y, .et al. , Anal Biochem, 2018, Dec 15;563:61-66 PMID: 30316750

Alisa A. Garaeva, .et al. , Cell Cycle, 2016, 15(1): 64-71 PMID: 26771712

A G Evstafieva, .et al. , Cell Death Dis., 2014, 5(11): e1511. PMID: 25375376

Biological Activity

Discription	MDM2 antagonist nutlin-3 is a potent inducer of apoptosis.

Product Information

Catalog Num	A10657
Formula	C30H30Cl2N4O4
Molecular Weight	581.5
CAS Number	548472-68-0
SMILES	CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	87 mg/mL (149.61 mM)
	Water	Insoluble
	Ethanol	26 mg/mL (44.71 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.2 mL	85.98 mL	171.97 mL
0.5 mM	3.44 mL	17.2 mL	34.39 mL
1 mM	1.72 mL	8.6 mL	17.2 mL
5 mM	0.34 mL	1.72 mL	3.44 mL

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