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Nutlin-3

Catalog No.: A10657
Mdm2 antagonist
Adooq's Nutlin-3 has been cited by 4 publications
MDM2 antagonist nutlin-3 is a potent inducer of apoptosis.
Nutlin-3
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Product Name Price Stock Qty
Nutlin-3 5mg
Special Price $52.00 Regular Price $65.00
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Nutlin-3 25mg
Special Price $160.00 Regular Price $200.00
In stock
Nutlin-3 50mg
Special Price $288.00 Regular Price $360.00
In stock
Nutlin-3 100mg
Special Price $448.00 Regular Price $560.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Nutlin-3 has been cited by 4 publications
  • Maxime Parisotto, .et al. , J Exp Med, 2018, Jun 4; 215(6): 1749-1763 PMID: 29743291
  • Ohmuro-Matsuyama Y, .et al. , Anal Biochem, 2018, Dec 15;563:61-66 PMID: 30316750
  • Alisa A. Garaeva, .et al. , Cell Cycle, 2016, 15(1): 64-71 PMID: 26771712
  • A G Evstafieva, .et al. , Cell Death Dis., 2014, 5(11): e1511. PMID: 25375376
    • Biological Activity
    Discription MDM2 antagonist nutlin-3 is a potent inducer of apoptosis.
    Product Information
    Catalog Num A10657
    Formula C30H30Cl2N4O4
    Molecular Weight 581.5
    CAS Number 548472-68-0
    SMILES CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro DMSO 87 mg/mL (149.61 mM)
    Water Insoluble
    Ethanol 26 mg/mL (44.71 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 17.2 mL 85.98 mL 171.97 mL
    0.5 mM 3.44 mL 17.2 mL 34.39 mL
    1 mM 1.72 mL 8.6 mL 17.2 mL
    5 mM 0.34 mL 1.72 mL 3.44 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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    Apoptosis > MDM2
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