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Mdm2 antagonist

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Catalog No. A10657

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Nutlin-3 5mg A10657-5

Regular Price: $65.00

Special Price: $58.50

Nutlin-3 25mg A10657-25

Regular Price: $200.00

Special Price: $180.00

Nutlin-3 50mg A10657-50

Regular Price: $360.00

Special Price: $324.00

Nutlin-3 100mg A10657-100

Regular Price: $560.00

Special Price: $504.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

MDM2 antagonist nutlin-3 is a potent inducer of apoptosis.


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Publications citing Adooq Products
Nutlin-3 Citations (4)
  • Maxime Parisotto, .et al. PTEN deletion in luminal cells of mature prostate induces replication stress and senescence in vivo, J Exp Med, 2018, Jun 4; 215(6): 1749-1763 PMID: 29743291
  • Ohmuro-Matsuyama Y, .et al. Evaluation of protein-ligand interactions using the luminescent interaction assay FlimPIA with streptavidin-biotin linkage, Anal Biochem, 2018, Dec 15;563:61-66 PMID: 30316750
  • Alisa A. Garaeva, .et al. Mitochondrial dysfunction induces SESN2 gene expression through Activating Transcription Factor 4, Cell Cycle, 2016, 15(1): 64-71 PMID: 26771712
  • A G Evstafieva, .et al. A sustained deficiency of mitochondrial respiratory complex III induces an apoptotic cell death through the p53-mediated inhibition of pro-survival activities of the activating transcription factor 4, Cell Death Dis., 2014, 5(11): e1511. PMID: 25375376

Chemical Information

Catalog Num A10657
Actions Antagonist
M. Wt 581.5
Formula C30H30Cl2N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 548472-68-0
Synonyms Nutlin3

Biological Activity

MDM2 antagonist nutlin-3 is a potent inducer of apoptosis.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.2 mL 85.98 mL 171.97mL
0.5 mM 3.44 mL 17.2 mL 34.39 mL
1 mM 1.72 mL 8.6 mL 17.2 mL
5 mM 0.34 mL 1.72 mL 3.44 mL

*The above data is based on the productmolecular weight 581.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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