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Biological Activity
Nutlin carboxylic acid (MDM2 ligand 1) is the Nutlin 3-based MDM2 ligand. Nutlin carboxylic acid (MDM2 ligand 1) can be connected to the ligand for protein by a linker to form PROTACs.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.64 mL | 78.18 mL | 156.36 mL |
| 0.5 mM | 3.13 mL | 15.64 mL | 31.27 mL |
| 1 mM | 1.56 mL | 7.82 mL | 15.64 mL |
| 5 mM | 0.31 mL | 1.56 mL | 3.13 mL |
*The above data is based on the productmolecular weight 639.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18917 |
|---|---|
| CAS No. | 2249750-27-2 |
| Formula | C32H32Cl2N4O6 |
| M. Wt | 639.53 |
| Purity | >98% |
| Synonyms | 0 |
| SMILES | O=C(N1C(C2=C(C=C(C=C2)OC)OC(C)C)=N[C@@H](C3=CC=C(C=C3)Cl)[C@H]1C4=CC=C(C=C4)Cl)N5CC(N(CC(O)=O)CC5)=O.[Relative stereochemistry] |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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