Fig. 1 · Structure
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NVP-EVS459
FR-targeting Radioconjugate
NVP-EVS459 is a Folate Receptor (FR)-targeting radioconjugate that binds selectively to FR-expressing cells. Labeled with 177Lu, it is utilized in imaging and diagnosis of tumors, facilitating research on cancer therapeutics and personalized medicine approaches. This compound serves as a valuable tool for the study of folate receptor-targeted therapies in oncology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2852679-40-2 |
| Applications | FR-targeting Radioconjugate |
| Formula | C55H69N15O16 |
| Molecular Weight | 1196.23 |
| SMILES | O=C1C=2C(NC=C(CNC3=CC=C(C(N[C@@H](CCCCNC(C[C@H](NC([C@H](CC4=CC5=C(C=C4)C=CC=C5)NC(CNC(CN6CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC6)=O)=O)=O)C(O)=O)=O)C(O)=O)=O)C=C3)N2)=NC(N)=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.