Fig. 1 · Structure
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NVP-LBX192
Glucokinase Activator
NVP-LBX192 is a potent glucokinase activator with a K(a) of 39 nM. This compound effectively lowers glucose levels, making it an important tool for studying metabolic diseases, particularly type 2 diabetes. Researchers can utilize NVP-LBX192 to explore its therapeutic potential and mechanisms of action in glucose homeostasis and insulin sensitivity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 866772-52-3 |
| Applications | Glucokinase Activator |
| Formula | C26H33N5O4S2 |
| Molecular Weight | 543.70 |
| SMILES | O=C(NC1=NC2=CC=C(OC)N=C2S1)[C@H](CC3CCCC3)C4=CC=C(S(=O)(N5CCN(C)CC5)=O)C=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.