Fig. 1 · Structure
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NVS MLLT-1
MLLT1 Inhibitor
NVS MLLT-1 is a potent and selective inhibitor of MLLT1, exhibiting Kd values of 0.18 μM for wild-type and 0.24 μM and 0.22 μM for T1 and T3 mutants, respectively. This compound serves as a valuable chemical probe for investigating MLLT1's role in oncogenic pathways. Its application is crucial for understanding the molecular mechanisms involved in various cancers, providing insights into potential therapeutic strategies targeting MLLT1-related aberrations.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2561471-13-2 |
| Applications | MLLT1 Inhibitor |
| Formula | C23H23N5O |
| Molecular Weight | 385.46 |
| SMILES | O=C(C1=CC2=C(C=NC=C2)C=C1)NC3=CC=C4C(NC(CN5[C@H](CCC5)C)=N4)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.