O-Arachidonoyl glycidol-d5

Catalog No.: A59359
Stable Isotope
O-Arachidonoyl glycidol-d5 is a deuterium-labeled analog of O-Arachidonoyl glycidol, serving as a stable isotope for research applications. This compound functions primarily by inhibiting the hydrolysis of 2-oleoylglycerol (2-OG) with an IC50 of 4.5 μM, impacting lipid signaling pathways. Additionally, O-Arachidonoyl glycidol-d5 inhibits anandamide hydrolysis, demonstrating IC50 values of 19 μM and 12 μM, respectively. This reagent is valuable for studies in lipid metabolism and endocannabinoid signaling.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionO-Arachidonoyl glycidol-d5 is a deuterium-labeled analog of O-Arachidonoyl glycidol, serving as a stable isotope for research applications. This compound functions primarily by inhibiting the hydrolysis of 2-oleoylglycerol (2-OG) with an IC50 of 4.5 μM, impacting lipid signaling pathways. Additionally, O-Arachidonoyl glycidol-d5 inhibits anandamide hydrolysis, demonstrating IC50 values of 19 μM and 12 μM, respectively. This reagent is valuable for studies in lipid metabolism and endocannabinoid signaling.
Product Information
Catalog NumA59359
FormulaC23H31D5O3
Molecular Weight365.56
CAS Number2519458-54-7
SMILESO=C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)OC([2H])(C1(OC1([2H])[2H])[2H])[2H]
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