Fig. 1 · Structure

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O-Arachidonoyl glycidol

2-AG Analog

O-Arachidonoyl glycidol is a 2-arachidonoylglycerol (2-AG) analog that acts primarily by inhibiting the hydrolysis of 2-oleoylglycerol (2-OG), exhibiting an IC50 value of 4.5 µM. This compound is also capable of blocking 2-OG hydrolysis in membrane fractions and inhibits anandamide hydrolysis with IC50 values of 19 µM and 12 µM, respectively. O-Arachidonoyl glycidol is valuable for research applications focusing on endocannabinoid signaling and lipid metabolism.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 439146-24-4
Applications 2-AG Analog
Formula C23H36O3
Molecular Weight 360.53
SMILES
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(OCC1CO1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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