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O-Demethyl Lenvatinib

Lenvatinib Metabolite

O-Demethyl Lenvatinib is a significant metabolite of Lenvatinib, a multi-targeted oral tyrosine kinase inhibitor. It primarily targets vascular endothelial growth factor receptors (VEGFR1-3), fibroblast growth factor receptors (FGFR1-4), platelet-derived growth factor receptor (PDGFR), KIT, and RET, demonstrating potent antitumor activity. This reagent is valuable for research applications that explore the biological effects and pharmacokinetics of Lenvatinib in various cancer models.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	417717-04-5
Applications	Lenvatinib Metabolite
Formula	C₂₀H₁₇ClN₄O₄
Molecular Weight	412.83
SMILES	O=C(C1=C(O)C=C2N=CC=C(OC3=CC=C(NC(NC4CC4)=O)C(Cl)=C3)C2=C1)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.