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O-Demethylrotenone

Rotenone Derivative

O-Demethylrotenone is a derivative of rotenone, primarily acting as a mitochondrial complex I inhibitor. It demonstrates acute intraperitoneal toxicity, with an LD50 of 8.0 mg/kg in Mus musculus. This compound is valuable for research focused on investigating the mechanisms of mitochondrial dysfunction and toxicity in various biological models.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	36375-21-0
Applications	Rotenone Derivative
Formula	C₂₂H₂₀O₆
Molecular Weight	380.39
SMILES	O=C1[C@@]2([H])C3=CC(OC)=C(O)C=C3OC[C@@]2([H])OC4=C(C[C@@H](O5)C(C)=C)C5=CC=C41

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.