Fig. 1 · Structure
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O-Desmethyltramadol (hydrochloride)
Tramadol Active Metabolite
O-Desmethyltramadol hydrochloride is the primary active metabolite of tramadol, functioning primarily by activating the µ-opioid receptor (µ-OR). This compound effectively crosses the blood-brain barrier, contributing to its significant analgesic properties. O-Desmethyltramadol is utilized in various research applications focused on pain management and opioid pharmacology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 185453-02-5 |
| Applications | Tramadol Active Metabolite |
| Formula | C15H24ClNO2 |
| Molecular Weight | 285.81 |
| SMILES | OC1=CC=CC([C@]2(O)[C@@H](CN(C)C)CCCC2)=C1.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.