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O-GlcNAcase-IN-3

OGA Inhibitor

O-GlcNAcase-IN-3 is an inhibitor of O-GlcNAcase (OGA), an enzyme involved in the hydrolysis of O-linked N-acetylglucosamine (O-GlcNAc) from target proteins. This compound demonstrates significant potential in Alzheimer's Disease research by modulating O-GlcNAc levels, which can influence neuronal function and pathology. Its role in the regulation of glycosylation processes makes it a valuable tool for studying neurodegenerative disorders and their underlying mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2760514-33-6
Applications	OGA Inhibitor
Formula	C₂₀H₂₆FN₅O₉S
Molecular Weight	531.51
SMILES	COC1=NC=NC(O[C@@H]2C[C@H](C)N(CC3=C(F)N=C(NC(C)=O)S3)C2)=C1.O[C@H]([C@@H](O)C(O)=O)C(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.