Fig. 1 · Structure
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OAT1/3-IN-1
OAT1/3 Inhibitor
OAT1/3-IN-1 is a dual inhibitor of the organic anion transporters OAT1 and OAT3. This compound has demonstrated the ability to reverse the toxicity of cysteine-mercury complexes in HEK-OAT1 cells at a concentration of 10 μM, indicating potential protective effects against kidney damage. OAT1/3-IN-1 is a valuable tool for investigating mercury-induced nephrotoxicity and related renal pathologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 38393-73-6 |
| Applications | OAT1/3 Inhibitor |
| Formula | C16H12O6 |
| Molecular Weight | 300.26 |
| SMILES | O=C1C2=CC=C(C(O)=C2C(C3=C1C=C(C)C(O)=C3OC)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.