Fig. 1 · Structure
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Obafistat
AKR1C3 Iinhibitor
Obafistat is a potent inhibitor of the aldo-keto reductase AKR1C3, exhibiting an IC50 of 1.2 nM for human AKR1C3. This compound demonstrates significant potential in regulating steroid metabolism and may be useful in research focused on various diseases, including cancer and metabolic disorders. Its high affinity and selectivity make Obafistat an important tool for investigating the role of AKR1C3 in physiological and pathological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2160582-57-8 |
| Applications | AKR1C3 Iinhibitor |
| Formula | C15H16FN5O3S |
| Molecular Weight | 365.38 |
| SMILES | O=C(N1CC(N2S(=O)(C3=CC=CC(F)=C3)=O)CCC2C1)C4=CN=NN4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.