Obatoclax mesylate (GX15-070)

Catalog No.: A10665

Bcl-2 Inhibitor

Obatoclax mesylate (GX15-070)

Obatoclax mesylate (GX15-070) Chemical Structure

CAS NO. 803712-79-0

Bcl-2 homology domain-3 (BH3) mimetic,antagonize all antiapoptotic Bcl-2 family proteins (average IC50, 3 umol/L), including Mcl-1 (IC50, 2.9 umol/L) and Bfl-1 (IC50, 5 umol/L).

Availability: In stock

Package Price Qty
5 mg

Regular Price: $80.00

Special Price $72.00

10 mg

Regular Price: $130.00

Special Price $117.00

25 mg

Regular Price: $190.00

Special Price $171.00

50 mg

Regular Price: $260.00

Special Price $234.00

10mM * 1mL in DMSO

Regular Price: $85.00

Special Price $76.50

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Bcl-2 homology domain-3 (BH3) mimetic,antagonize all antiapoptotic Bcl-2 family proteins (average IC50, 3 umol/L), including Mcl-1 (IC50, 2.9 umol/L) and Bfl-1 (IC50, 5 umol/L).
Targets
Bcl-2 (Cell-free assay)
0.22 μM(Ki)
In vitro (25°C) DMSO 83 mg/mL (200.73 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.18 mL 120.92 mL 241.84 mL
0.5 mM 4.84 mL 24.18 mL 48.37 mL
1 mM 2.42 mL 12.09 mL 24.18 mL
5 mM 0.48 mL 2.42 mL 4.84 mL

*The above data is based on the productmolecular weight 413.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10665
Actions Inhibitor
M. Wt 413.5
Formula C20H19N3O.CH4O3S
Solubility DMSO>83mg/mL Water<1mg/mL Ethanol<1mg/mL
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 803712-79-0
Synonyms N/A
SMILES CC1=CC(=C(N1)/C=C/2\C(=C/C(=C\3/C=C4C=CC=CC4=N3)/N2)OC)C.CS(=O)(=O)O

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