Obatoclax mesylate (GX15-070)

Name: Obatoclax mesylate (GX15-070)
SKU: A10665
Price: 35 USD
Rating: 5 (4 reviews)

Catalog No.: A10665

Bcl-2 Inhibitor

Adooq's Obatoclax mesylate (GX15-070) has been cited by 4 publications

Bcl-2 homology domain-3 (BH3) mimetic,antagonize all antiapoptotic Bcl-2 family proteins (average IC50, 3 umol/L), including Mcl-1 (IC50, 2.9 umol/L) and Bfl-1 (IC50, 5 umol/L).

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Grouped product items
Size	Price	Stock
5mg	$35.00	In stock
10mg	$60.00	In stock
25mg	$120.00	In stock
50mg	$220.00	In stock
100mg	$370.00	In stock
*10mM 1mL in DMSO**	$40.00	In stock
Bulk Size	Bulk Discount

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Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's Obatoclax mesylate (GX15-070) has been cited by 4 publications

Ashlyn Parkhurst, .et al. , Cell Death Dis, 2022, Apr 28;13(4):410 PMID: 35484114

Silva S, .et al. , Sci Rep, 2019, Nov 27;9(1):17703 PMID: 31776405

Chi-Hung R. Or, .et al. , Int J Mol Sci, 2016, Jan; 18(1): 44 PMID: 28035994

P Geserick, .et al. , Cell Death Dis., 2014, 5(9): e1412 PMID: 25210795

Biological Activity

Discription

Bcl-2 homology domain-3 (BH3) mimetic,antagonize all antiapoptotic Bcl-2 family proteins (average IC50, 3 umol/L), including Mcl-1 (IC50, 2.9 umol/L) and Bfl-1 (IC50, 5 umol/L).

Targets

Target	Value

Product Information

Catalog Num	A10665
Formula	C20H19N3O.CH4O3S
Molecular Weight	413.5
CAS Number	803712-79-0
SMILES	CC1=CC(=C(N1)/C=C/2\C(=C/C(=C\3/C=C4C=CC=CC4=N3)/N2)OC)C.CS(=O)(=O)O
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	81 mg/mL (195.89 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.18 mL	120.92 mL	241.84 mL
0.5 mM	4.84 mL	24.18 mL	48.37 mL
1 mM	2.42 mL	12.09 mL	24.18 mL
5 mM	0.48 mL	2.42 mL	4.84 mL

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