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Octreotide-d8

Catalog No.: A33057
Stable Isotope
Octreotide-d8 is a deuterium-labeled analog of the somatostatin receptor agonist, Octreotide. It selectively binds to somatostatin receptor subtypes 2, 3, and 5, enhancing Gi signaling and decreasing intracellular cAMP levels. Octreotide-d8 exhibits notable antitumor activity and is instrumental in apoptosis studies, making it a valuable tool for research on acromegaly and related diseases.
Octreotide-d8 1240797-41-4 Stable Isotope
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionOctreotide-d8 is a deuterium-labeled analog of the somatostatin receptor agonist, Octreotide. It selectively binds to somatostatin receptor subtypes 2, 3, and 5, enhancing Gi signaling and decreasing intracellular cAMP levels. Octreotide-d8 exhibits notable antitumor activity and is instrumental in apoptosis studies, making it a valuable tool for research on acromegaly and related diseases.
Product Information
Catalog NumA33057
FormulaC49H58D8N10O10S2
Molecular Weight1027.29
CAS Number1240797-41-4
SMILESO=C([C@@H](NC([C@@H](CSSC[C@H](NC([C@](NC([C@@H](NC1=O)CCCCN)=O)([H])[C@H](O)C)=O)C(NC(CO)C(O)C)=O)NC(C(N)([2H])C([2H])([2H])C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])=O)=O)CC3=CC=CC=C3)N[C@H]1CC4=CNC5=CC=CC=C45
SynonymsSMS 201-995-d8
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Isotope-Labeled Compounds