Oditrasertib

Catalog No.: A25064
RIPK1 Inhibitor
Oditrasertib is a selective reversible inhibitor of receptor-interacting protein kinase 1 (RIPK1), demonstrating oral bioavailability and the ability to penetrate the blood-brain barrier. It is primarily utilized in research related to chronic inflammatory diseases of the central nervous system, including amyotrophic lateral sclerosis and multiple sclerosis. Oditrasertib provides valuable insights into the mechanisms of RIPK1-mediated signaling pathways, aiding in the development of potential therapeutic strategies for these conditions.
Grouped product items
Size Price Stock Qty
1mg
$55.00
In stock
5mg
$135.00
In stock
10mg
$200.00
In stock
25mg
$335.00
In stock
50mg
$470.00
In stock
100mg
$630.00
In stock
500mg
$1,240.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionOditrasertib is a selective reversible inhibitor of receptor-interacting protein kinase 1 (RIPK1), demonstrating oral bioavailability and the ability to penetrate the blood-brain barrier. It is primarily utilized in research related to chronic inflammatory diseases of the central nervous system, including amyotrophic lateral sclerosis and multiple sclerosis. Oditrasertib provides valuable insights into the mechanisms of RIPK1-mediated signaling pathways, aiding in the development of potential therapeutic strategies for these conditions.
Product Information
Catalog NumA25064
FormulaC14H15F2N3O2
Molecular Weight295.28
CAS Number2252271-93-3
SMILESN#CC1=CN=CC2=C1OCCN(C2)C(C(C)(C(F)F)C)=O
SynonymsSAR443820; DNL788
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