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ODN INH 18

Inhibitory ODN

ODN INH 18 is a linear 24-mer inhibitory oligodeoxynucleotide (INH-ODN) designed to modulate immune responses through the inhibition of toll-like receptor 9 (TLR9) signaling. This reagent features a specific 5' sequence followed by a random stretch of 12 nucleotides, chosen to minimize secondary structure formation. ODN INH 18 exhibits significant inhibitory potency for TLR9 ligand-induced interferon-alpha (IFN-α) production, making it valuable for research applications focused on immunomodulation and therapeutic development against autoimmune diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1934318-43-0
Applications	Inhibitory ODN
Molecular Weight	7723.29

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.