OF-1

Catalog No.: A16000

BRPF1B/BRPF2 bromodomain inhibitor

OF-1

OF-1 Chemical Structure

CAS NO. 19973-83-4

OF-1 is a chemical probe for BRPF bromodomains. OF-1 has been shown to bind to BRPF1B with a KD of 100 nM (ITC), to BRPF2 with a KD of 500 nM (ITC) and to BRPF3 with a KD of 2.4 uM (ITC).

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$120.00
50 mg
$520.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

OF-1 is a chemical probe for BRPF bromodomains. OF-1 has been shown to bind to BRPF1B with a KD of 100 nM (ITC), to BRPF2 with a KD of 500 nM (ITC) and to BRPF3 with a KD of 2.4 uM (ITC).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.71 mL 113.56 mL 227.11 mL
0.5 mM 4.54 mL 22.71 mL 45.42 mL
1 mM 2.27 mL 11.36 mL 22.71 mL
5 mM 0.45 mL 2.27 mL 4.54 mL

*The above data is based on the productmolecular weight 440.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A16000
Actions Inhibitor
M. Wt 440.31
Formula C17H18BrN3O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 19973-83-4
Synonyms OF1, OF 1
SMILES O=S(C1=CC=C(Br)C=C1C)(NC2=C(OC)C=C(N3C)C(N(C)C3=O)=C2)=O

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