OG-L002

Catalog No.: A13246

LSD1 inhibitor

OG-L002

OG-L002 Chemical Structure

CAS NO. 1357302-64-7

OG-L002 is a potent and specific LSD1 inhibitor with IC50 of 20 nM, exhibiting 36- and 69-fold selectivity over MAO-B and MAO-A, respectively.

Availability: In stock

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5 mg

Regular Price: $90.00

Special Price $72.00

10 mg

Regular Price: $150.00

Special Price $120.00

25 mg

Regular Price: $280.00

Special Price $224.00

50 mg

Regular Price: $500.00

Special Price $400.00

10mM * 1mL in DMSO

Regular Price: $106.00

Special Price $84.80

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Biological Activity

OG-L002 is a potent and specific LSD1 inhibitor with IC50 of 20 nM, exhibiting 36- and 69-fold selectivity over MAO-B and MAO-A, respectively.
Targets
LSD1 (Cell-free assay)
20 nM
In vitro (25°C) DMSO 41 mg/mL (181.99 mM)
Water Insoluble
Ethanol 17 mg/mL (75.45 mM)
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 19 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 38.2 mL 191.02 mL 382.04 mL
0.5 mM 7.64 mL 38.2 mL 76.41 mL
1 mM 3.82 mL 19.1 mL 38.2 mL
5 mM 0.76 mL 3.82 mL 7.64 mL

*The above data is based on the productmolecular weight 261.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13246
Actions Inhibitor
CAS No. 1357302-64-7
Formula C15H15NO.HCl
M. Wt 261.75
Purity >98%
Synonyms OGL002, OG L002
SMILES CCOc1cc(ccc1Nc1ncc2c(n1)n(C)c1ccccc1c(=O)n2C)N1CCC(CC1)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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