Fig. 1 · Structure
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OGG1-IN-08
OGG1 Inhibitor
OGG1-IN-08 is a selective inhibitor of 8-oxoguanine DNA glycosylase-1 (OGG1), exhibiting an IC50 value of 0.22 μM. This compound effectively reduces both the glycosylase and lyase activities of OGG1, making it a valuable tool for investigating oxidative DNA damage repair mechanisms. Research applications include studies on DNA repair pathways and the role of OGG1 in various biological processes and disease states.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 350997-39-6 |
| Applications | OGG1 Inhibitor |
| Formula | C9H6Cl2N2OS |
| Molecular Weight | 261.13 |
| SMILES | O=C(C1=C(Cl)C2=C(Cl)C=CC=C2S1)NN |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.