Fig. 1 · Structure
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OJT008
MtMetAP1c Inhibitor
OJT008 is an inhibitor of MtMetAP1c, specifically targeting this enzyme involved in protein maturation. It demonstrates inhibitory activity against NiCl2- and CoCl2-activated MtMetAP1c, with IC50 values of 11 μM and 40 μM, respectively. This compound is valuable for research applications related to tuberculosis, providing insights into the role of MtMetAP1c in mycobacterial pathogenesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 256370-29-3 |
| Applications | MtMetAP1c Inhibitor |
| Formula | C18H17ClN4 |
| Molecular Weight | 324.81 |
| SMILES | CN(C1=NC(C2=NC=CC=C2)=NC(C)=C1Cl)CC3=CC=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.