Fig. 1 · Structure

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Olmesartan methyl ester

Angiotensin AT1 Receptor Antagonist

Olmesartan methyl ester serves as an intermediate in the synthesis of Olmesartan medoxomil, a highly selective antagonist of the angiotensin AT1 receptor. This compound exhibits a potent inhibitory effect, with an IC50 value of 66.2 μM. It is primarily utilized in research focused on hypertension, cardiovascular diseases, and related physiological studies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1347262-29-6
Applications Angiotensin AT1 Receptor Antagonist
Formula C25H28N6O3
Molecular Weight 460.53
SMILES
O=C(C1=C(C(C)(O)C)N=C(CCC)N1CC2=CC=C(C3=CC=CC=C3C4=NNN=N4)C=C2)OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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