Fig. 1 · Structure
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Olodaterol hydrochloride
β2-AR Agonist
Olodaterol hydrochloride is a selective long-acting β2-adrenoceptor (β2-AR) agonist, demonstrating an EC50 of 0.1 nM and a pKi of 9.14 for the human β2-adrenoceptor. This compound exhibits key biological activity by promoting bronchial dilation, making it an important reagent for the treatment of chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis. Olodaterol is primarily utilized in research focused on respiratory disorders and therapeutic interventions targeting the β2-AR pathway.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 869477-96-3 |
| Applications | β2-AR Agonist |
| Formula | C21H27ClN2O5 |
| Molecular Weight | 422.90 |
| Synonyms | BI1744 hydrochloride |
| SMILES | O=C1NC2=CC(O)=CC([C@@H](O)CNC(C)(C)CC3=CC=C(OC)C=C3)=C2OC1.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.