Fig. 1 · Structure
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Olpadronic acid
Bone Resorption Inhibitor
Olpadronic acid, an amino-bisphosphonate, primarily targets bone resorption by inhibiting osteoclast activity. It demonstrates significant efficacy in preventing bone destruction and tumor growth in skeletal prostate cancer mouse models. This compound is applicable in research focused on osteoporosis, malignancies, and rheumatoid arthritis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 63132-39-8 |
| Applications | Bone Resorption Inhibitor |
| Formula | C5H15NO7P2 |
| Molecular Weight | 263.12 |
| Synonyms | Olpadronate; OLP |
| SMILES | O=P(O)(C(CCN(C)C)(P(O)(O)=O)O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.