Fig. 1 · Structure
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Olsalazine Disodium
Anticancer/Antiinflammation Agent
Olsalazine Disodium is an orally active prodrug of 5-aminosalicylic acid (5-ASA), primarily targeting anti-inflammatory mechanisms. It demonstrates significant inhibition of cell proliferation and promotes apoptosis, making it useful in cancer research. Additionally, Olsalazine Disodium decreases Disease Activity Index (DAI) and myeloperoxidase (MPO) activity, while downregulating inflammatory cytokine levels. This compound is applicable for studies in inflammation, cancer, and metabolic diseases, particularly in colorectal cancer and inflammatory bowel disease (IBD).
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 6054-98-4 |
| Applications | Anticancer/Antiinflammation Agent |
| Formula | C14H8N2Na2O6 |
| Molecular Weight | 346.20 |
| SMILES | O=C(O[Na])C1=C(O)C=CC(/N=N/C2=CC(C(O[Na])=O)=C(O)C=C2)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.