Fig. 1 · Structure
Documents & Downloads
OM-1700
Tankyrase Inhibitor
OM-1700 is a potent tankyrase inhibitor, exhibiting IC50 values of 127 nM for tankyrase 1 and 14 nM for tankyrase 2. This compound effectively reduces cell proliferation in the colon cancer cell line COLO 320DM, with a GI50 of 650 nM. OM-1700 serves as a valuable tool for investigating the role of tankyrase in cancer biology and potential therapeutic applications.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2406276-78-4 |
| Applications | Tankyrase Inhibitor |
| Formula | C25H23FN6O2 |
| Molecular Weight | 458.49 |
| SMILES | FC1=[C@](C=CC=C1)[N@]2C([C@]3([H])C[C@H](C3)NC(C4=CC=CC=N4)=O)=NN=C2C5=CC=C(C=N5)OCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.