Fig. 1 · Structure
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Omeprazole sulfone
Ulcer Healing Supporter
Omeprazole sulfone is a primary metabolite of omeprazole that functions as an ulcer healing supporter. It enhances the migration of gastric epithelial cells under baseline conditions and counteracts the inhibitory effects of Indomethacin on cell migration, promoting optimal gastric health. Omeprazole sulfone does not affect cell proliferation or upregulate COX-2 expression, nor does it activate key signaling pathways. Its mechanism provides a potential avenue for research into gastric ulcer repair and related therapeutic applications under non-acid-dependent conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 88546-55-8 |
| Applications | Ulcer Healing Supporter |
| Formula | C17H19N3O4S |
| Molecular Weight | 361.42 |
| Synonyms | Omeprazole sulphone |
| SMILES | CC(C(OC)=C(C)C=N1)=C1CS(C2=NC3=CC=C(OC)C=C3N2)(=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.