Onc112

Name: Onc112
Brand: Adooq Bioscience
SKU: A48766
Rating: 5 (288 reviews)

Catalog No.: A48766

Antimicrobial Peptide

Onc112 is a proline-rich antimicrobial peptide that primarily targets Gram-negative bacteria. It exerts its biological activity by inhibiting translation, specifically by blocking and destabilizing the initiation complex. This mechanism makes Onc112 a valuable tool for research applications focusing on bacterial resistance and the development of novel antimicrobial strategies.

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Onc112 1273548-87-0 Antimicrobial Peptide

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Biological Activity

Description	Onc112 is a proline-rich antimicrobial peptide that primarily targets Gram-negative bacteria. It exerts its biological activity by inhibiting translation, specifically by blocking and destabilizing the initiation complex. This mechanism makes Onc112 a valuable tool for research applications focusing on bacterial resistance and the development of novel antimicrobial strategies.

Product Information

Catalog Num	A48766
Formula	C109H177N37O24
Molecular Weight	2389.81
CAS Number	1273548-87-0
Sequence	Val-Asp-Lys-Pro-Pro-Tyr-Leu-Pro-Arg-Pro-Arg-Pro-Pro-Arg-{d-Arg}-Ile-Tyr-Asn-{d-Arg}-NH2
Sequence shortening	VDKPPYLPRPRPPRrIYNr-NH2
SMILES	C(=O)([C@H]1N(C([C@@H](NC(=O)[C@H]2N(C([C@@H](NC(=O)[C@H]3N(C([C@@H](NC([C@@H](NC(=O)[C@H]4N(C(=O)[C@H]5N(C([C@@H](NC([C@@H](NC([C@H](C(C)C)N)=O)CC(O)=O)=O)CCCCN)=O)CCC5)CCC4)CC6=CC=C(O)C=C6)=O)CC(C)C)=O)CCC3)CCCNC(=N)N)=O)CCC2)CCCNC(=N)N)=O)CCC1)N7[C@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@@H](CC8=CC=C(O)C=C8)C(N[C@H](C(N[C@H](CCCNC(=N)N)C(N)=O)=O)CC(N)=O)=O)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC7

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