Fig. 1 · Structure

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OncoACP3

ACP3 Ligand

OncoACP3 is a potent small-molecule ligand targeting prostatic acid phosphatase (ACP3) with an IC50 of 0.30 nM. Its modular structure facilitates the effective delivery of therapeutic payloads. Following radiolabeling with Lu-177, OncoACP3 shows selective accumulation in ACP3-expressing tumors, allowing for targeted radiation therapy with extended retention times. This compound is particularly valuable for research focused on prostate cancer treatment and targeted therapy development.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 3084147-81-6
Applications ACP3 Ligand
Formula C60H81N12O13P
Molecular Weight 1209.33
SMILES
OC(CN1CCN(CC(NCCCCCCNC([C@H]2N(C(CN(CC3=CC=CC=C3)CC4=CC=CC=C4)=O)C[C@@H](N5N=NC(COC6=CC=C(C(NCC7=CC=CC=C7)P(O)(O)=O)C=C6)=C5)C2)=O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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