Fig. 1 · Structure

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ONCOII

Cat. No. A55075 CAS 1263564-94-8

Mps1 Inhibitor

ONCOII is a potent Mps1 inhibitor with an IC50 of 10.8 nM, primarily targeting the Mps1 kinase involved in cell division and checkpoint regulation. This reagent's efficacy is influenced by specific mutations in the Mps1 gene, as cells harboring such mutations show increased resistance to ONCOII. It is particularly useful in cancer research to study cell cycle dynamics and the effects of Mps1 modulation in tumorigenesis.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1263564-94-8
Applications Mps1 Inhibitor
Formula C24H25N7O
Molecular Weight 427.50
SMILES
N#CC1=CC=C(NC2=CC(OCC#N)=C(C3=CN(C)N=C3)C=C2)N=C1NC4CCCCC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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