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Onfekafusp alfa

Anticancer Agent

Onfekafusp alfa is a homotrimeric fusion protein designed from the L19 antibody scFv format linked to human tumor necrosis factor (TNF). This reagent exhibits significant anticancer activity, particularly in the context of malignant glioma research. It functions by targeting tumor cells, thereby enhancing local production of TNF and promoting anti-tumor immune responses. Researchers can utilize Onfekafusp alfa for investigations into targeted cancer therapies and understanding tumor microenvironments.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1957239-88-1
Applications	Anticancer Agent
Synonyms	L19TNF

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.