Fig. 1 · Structure
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OPC-4392
Antipsychotic Agent
OPC-4392 is an orally active presynaptic dopamine autoreceptor agonist and postsynaptic D2 receptor antagonist. This compound demonstrates significant antipsychotic activity by reversing Reserpine-induced dopamine depletion and inhibiting Apomorphine-induced stereotypic behaviors in murine models. OPC-4392 is a valuable reagent for research on antipsychotic therapies and the underlying mechanisms of dopamine modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 111073-34-8 |
| Applications | Antipsychotic Agent |
| Formula | C24H29N3O2 |
| Molecular Weight | 391.51 |
| SMILES | CC(C(C)=CC=C1)=C1N(CC2)CCN2CCCOC3=CC=C(C=CC4=O)C(N4)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.