Fig. 1 · Structure
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Opemalirsen sodium
APOL1 synthesis reducer
Opemalirsen sodium is an antisense oligonucleotide that specifically targets and reduces the synthesis of apolipoprotein L1 (APOL1). This compound is primarily utilized in research focusing on kidney disorders, providing insights into the molecular mechanisms underlying APOL1-related pathologies. Its ability to modulate APOL1 levels makes it a valuable tool for investigating therapeutic strategies in renal diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2639854-33-2 |
| Applications | APOL1 synthesis reducer |
| Molecular Weight | 5480.52 (free acid) |
| Synonyms | AZD2373 sodium; ION-972190 sodium |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
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| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.