Opnurasib (JDQ-443)

Name: Opnurasib (JDQ-443)
Brand: Adooq Bioscience
SKU: A24526
Rating: 5 (288 reviews)

Catalog No.: A24526

KRAS G12C inhibitor

Opnurasib (JDQ-443, also known as NVP-JDQ443) is an orally active, potent, selective, and covalent KRAS^G12C inhibitor, as described in patent WO2021120890A1. It exhibits strong antitumor activity in KRAS^G12C-driven cancer models.

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Opnurasib (JDQ-443) 2653994-08-0 KRAS G12C inhibitor

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Grouped product items
Size	Price	Stock
1mg	$108.00	In stock
5mg	$324.00	In stock
10mg	$552.00	In stock
50mg	$1,656.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	Opnurasib (JDQ-443, also known as NVP-JDQ443) is an orally active, potent, selective, and covalent KRAS^G12C inhibitor, as described in patent WO2021120890A1. It exhibits strong antitumor activity in KRAS^G12C-driven cancer models.

Product Information

Catalog Num	A24526
Formula	C29H28ClN7O
Molecular Weight	526.03
CAS Number	2653994-08-0
SMILES	O=C(C=C)N1CC2(C1)CC(N3N=C(C4=CC=C5C(C=NN5C)=C4)[C@]([C@]6=C(Cl)C(C)=CC7=C6C=NN7)=C3C)C2
Synonyms	NVP-JDQ443
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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