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Orazamide

AICA Orotate

Orazamide is an AICA orotate that primarily targets the downregulation of HMGB1 and RAGE proteins in liver tissue. This compound exhibits protective effects against liver damage induced by anti-TB drugs by inhibiting the secretion of inflammatory cytokines. Orazamide is suitable for research applications focused on hepatitis and liver cirrhosis, contributing valuable insights into liver inflammation and injury mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2574-78-9
Applications	AICA Orotate
Formula	C₉H₁₀N₆O₅
Molecular Weight	282.21
SMILES	O=C(C1=CC(NC(N1)=O)=O)O.O=C(C2=C(N)N=CN2)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.