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ORC-13661 hydrochloride

MET Channel Blocker

ORC-13661 hydrochloride is a potent MET channel blocker that provides protection for sensory hair cells. This compound effectively shields these cells from ototoxicity induced by aminoglycosides and cisplatin. ORC-13661 hydrochloride functions as a reversible blocker of mechanoelectrical transducer channels, making it a valuable tool for research focused on auditory protection and ototoxicity studies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Blocker
CAS Number	1979935-34-6
Applications	MET Channel Blocker
Formula	C₁₈H₂₀Cl₂N₄O₂S
Molecular Weight	427.35
SMILES	NC(C1=C(NC(NC2=CC=C(C=C2)Cl)=O)SC3=C1[C@](CC4)([H])N(C)[C@]4([H])C3)=O.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.