Fig. 1 · Structure
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Orcinol
Melanogenesis Inhibitor
Orcinol (3,5-Dihydroxytoluene) is a melanogenesis inhibitor targeting the MAPK/ERK signaling pathway. It effectively reduces melanogenesis in B16F10 cells by downregulating the expression of key melanogenic enzymes, including MITF, tyrosinase (TYR), TRP1, and DCT. Additionally, Orcinol demonstrates DPPH radical scavenging activity and can influence nitrogen balance in animal models. This compound is relevant for research applications in cancer and metabolic diseases, making it a valuable reagent in biochemical studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 504-15-4 |
| Applications | Melanogenesis Inhibitor |
| Formula | C7H8O2 |
| Molecular Weight | 124.14 |
| Synonyms | 3,5-Dihydroxytoluene |
| SMILES | OC1=CC(C)=CC(O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.