Orexin receptor antagonist 6 selectively targets the orexin 1 receptor (OX1) with a potent Ki of 8.5 nM and demonstrates more than 1180-fold selectivity for the OX2 receptor. This compound does not elicit conditioned place preference (CPP) or aversive effects and effectively inhibits CPP induced by psychoactive substances. Orexin receptor antagonist 6 is a valuable tool for investigating the role of orexin signaling in neurological diseases and related research applications.
Orexin receptor antagonist 6 selectively targets the orexin 1 receptor (OX1) with a potent Ki of 8.5 nM and demonstrates more than 1180-fold selectivity for the OX2 receptor. This compound does not elicit conditioned place preference (CPP) or aversive effects and effectively inhibits CPP induced by psychoactive substances. Orexin receptor antagonist 6 is a valuable tool for investigating the role of orexin signaling in neurological diseases and related research applications.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
