Fig. 1 · Structure
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Org 25543
GlyT Inhibitor
Org 25543 is a selective inhibitor of glycine transporter 2 (GlyT2), known for its analgesic effects. This compound demonstrates potential efficacy in alleviating chronic pain in preclinical models, making it a valuable tool for exploring pain modulation mechanisms. Its specificity for GlyT2 positions it as an important reagent for research in neurobiology and pain management applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 363628-88-0 |
| Applications | GlyT Inhibitor |
| Formula | C24H32N2O4 |
| Molecular Weight | 412.52 |
| SMILES | COC(C=C(C(NCC1(CCCC1)N(C)C)=O)C=C2OC)=C2OCC3=CC=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.