Fig. 1 · Structure
Documents & Downloads
Org 25935
GlyT1 Inhibitor
Org 25935 is a potent and selective inhibitor of glycine transporter 1 (GlyT1), exhibiting an IC50 value of 100 nM. This compound has been shown to significantly reduce ethanol intake and preference in rat models without affecting water consumption. Org 25935 serves as a valuable tool for investigating the mechanisms underlying alcohol dependence and abuse.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 949588-40-3 |
| Applications | GlyT1 Inhibitor |
| Formula | C21H26ClNO3 |
| Molecular Weight | 375.89 |
| SMILES | OC(CN(C)C[C@@H]1[C@H](C2=CC=CC=C2)C3=CC=C(OC)C=C3CC1)=O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.