Fig. 1 · Structure

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Org-9453 bromide

Neuromuscular Blocking Agent

Org-9453 bromide is a 17β-butyrate analogue of Vecuronium bromide, functioning as a short-acting non-depolarizing neuromuscular blocking agent. Its primary mechanism involves the competitive inhibition of motor end plate nicotinic acetylcholine receptors, leading to muscle relaxation. This compound is suitable for research applications related to muscle physiology, anesthesiology, and the development of neuromuscular blocking therapies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 160261-34-7
Applications Neuromuscular Blocking Agent
Formula C36H61BrN2O4
Molecular Weight 665.78
SMILES
C[C@@]12[C@](C[C@H]([N+]3(CCCCC3)C)[C@@H]2OC(CCC)=O)([H])[C@@]4([H])[C@]([C@@]5([C@@](C[C@H](OC(C)=O)[C@@H](N6CCCCC6)C5)([H])CC4)C)([H])CC1.[Br-]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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