Fig. 1 · Structure
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Org OD 02-0
mPRα Agonist
Org OD 02-0 is a specific agonist for the membrane progesterone receptor α (mPRα), with an IC50 value of 33.9 nM. It effectively activates MAPK activity and demonstrates the ability to inhibit prolactin (PRL) secretion in the pituitary gland. This compound is valuable for research applications involving hormone regulation and signaling pathways related to progesterone receptor activity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 13258-85-0 |
| Applications | mPRα Agonist |
| Formula | C22H30O2 |
| Molecular Weight | 326.47 |
| Synonyms | 10-Ethenyl-19-norprogesterone |
| SMILES | CC([C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C=C)[C@@]3([H])CC[C@]12C)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.