Org37684

Catalog No.: A29751
5-HT2C Receptor Agonist
Org37684 is a potent agonist of the 5-HT2C receptor, displaying a pEC50 value of 8.17. It demonstrates a preferential selectivity, being approximately 2.5 times more potent at the 5-HT2C receptor compared to the 5-HT2B receptor (pEC50=7.96) and ten times more potent than the 5-HT2A receptor (pEC50=7.11). This compound is utilized in research applications focused on the regulation of mood, appetite, and other neuropharmacological processes mediated by serotonin receptors.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionOrg37684 is a potent agonist of the 5-HT2C receptor, displaying a pEC50 value of 8.17. It demonstrates a preferential selectivity, being approximately 2.5 times more potent at the 5-HT2C receptor compared to the 5-HT2B receptor (pEC50=7.96) and ten times more potent than the 5-HT2A receptor (pEC50=7.11). This compound is utilized in research applications focused on the regulation of mood, appetite, and other neuropharmacological processes mediated by serotonin receptors.
Product Information
Catalog NumA29751
FormulaC14H20ClNO2
Molecular Weight269.77
CAS Number213007-95-5
SMILESCOC1=C(O[C@@H]2CNCC2)C3=C(CCC3)C=C1.[H]Cl
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