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Biological Activity
ORM-10103 is a specific inhibitor of the Na+/Ca2+ exchanger (NCX), which decreases the NCX current with estimated IC50s of 55 and 67 nM at -80 and at 20 mV, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.71 mL | 143.53 mL | 287.07 mL |
| 0.5 mM | 5.74 mL | 28.71 mL | 57.41 mL |
| 1 mM | 2.87 mL | 14.35 mL | 28.71 mL |
| 5 mM | 0.57 mL | 2.87 mL | 5.74 mL |
*The above data is based on the productmolecular weight 348.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18404 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 488847-28-5 |
| Formula | C20H16N2O4 |
| M. Wt | 348.35 |
| Purity | >98% |
| Synonyms | ORM10103, ORM 10103 |
| SMILES | O=[N+](C1=CN=C(OC2=CC=C3C(CCC(C4=CC=CC=C4)O3)=C2)C=C1)[O-] |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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